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Novel Drug Delivery Systems for Phytoconstituents discusses general
principles of drug targeting, construction material and
technological concerns of different phytoconstituent in delivery
systems. It focuses on the development of novel herbal formulations
and summarizes their method of preparation, type of active
ingredients, route of administration, biological activity and their
applications. It dicusses therapeutic activities of plant derived
chemicals, their limitations in clinical applications and novel
drug delivery solutions to overcome them to provide better
therapeutic effects with controlled and targeted drug delivery.
Focus on drug delivery of phytomolecules Act as bridge between
natural product scientist and clinical doctors Discusses mechanism
of poor bioavailability of herbal molecules Increases awareness
towards phytochemical efficacy Summarizes efficient novel delivery
systems-based formulations. It extensively covers the applications
of novel drug delivery systems including polymeric nanoparticles,
solid lipid nanoparticles, nanostructured lipid capsules,
liposomes, phytosomes, microsphere, transferosomes, and ethosomes.
Some chapters are especially focused on anticancer phytodrugs,
silymarin, andrographolide, berberine, and curcumin delivery with
special emphasis on their application.
This book comprises the select proceedings of the International
Conference on Emerging Trends in Mechanical and Industrial
Engineering (ICETMIE) 2019. The conference covers current trends in
thermal, design, industrial, production and other sub-disciplines
of mechanical engineering. This volume focuses on different
industrial and production engineering areas such as additive
manufacturing, rapid prototyping, computer aided engineering,
advanced manufacturing processes, manufacturing management and
automation, sustainable manufacturing systems, metrology,
manufacturing process optimization, operations research and
decision-making models, production planning and inventory control,
supply chain management, and quality engineering. The contents of
this book will be useful for students, researchers and other
professionals interested in industrial and production engineering.
This book focuses on the nature and properties of soils of Hindu
Kush-Himalayas and their management for agricultural land use. It
discusses all aspects of climatic variations and potential of
resources in the Himalayan region including examples from
Afghanistan, Bangladesh, Bhutan, China (Tibet), India, Myanmar,
Nepal and Pakistan. Chapters cover the geology of the parent
material of native soils, soils microbes, flora and fauna. Soil
classification has been given in detail to better understand the
nature of soils for judicious management strategies. The authors
present land use practices and suggestions for changes in land use
to benefit from the full potential of the soils in this region.
Their ultimate aim is to find ways of feeding the ever-increasing
population and raising the standard of life for the people living
in the Himalayan mountain region.
Cancer has emerged as an important health problem in the developed
and the developing countries. In the present investigation, 12
medicinal plants were evaluated against human cancer cell lines
from different origins and most significant results were displayed
by Apium graveolens, Holarrhena antidysenterica, Mallotus
philippinensis and Nardostachys jatamansi. Further, an active
ingredient namely Mallotoxin was isolated from the fruit part of
Mallotus philippinensis. This drug suppressed the proliferation of
eight human cancer cells from six different tissues and proved its
exceptionally remarkable in vitro anticancer efficiency.
As a part of the systematic and proteomic approach based
characterization of plant material with the advantage of producing
valuable informations of functional genomics for a general crop
improvement programme, leaves of holy medicinal-aromatic plant
Tulsi (Ocimum basilicum L.) were used as a source of proteins and a
model eukaryotic system. In this study, we developed a reliable
protocol for PEG mediated enrichment of low abundant cellular
proteins to increase their detection through 2 DE-SDS PAGE. I6% PEG
was found to be optimum for the precipitation of Ocimum protein.
Further, proteome proteins in different fractions were analysed
electrophoretically including 2- DE technique. These protocols may
also will helpful in further studies in basil proteomics and other
plants also.
During the post green revolution period, Punjab has emerged as an
agricultural development state. As a result, increased availability
of the farm level crop residues, green fodder due to intercrop
cultivation and the mill-level residues of the processed products
have strengthened the base for a diversified animal feed and eased
supply position that might have reduced the cost for rearing the
animals. While on the other hand, growing urbanization and income
levels thereby increased purchasing power, higher literacy there by
health and nutrition concerns, changing life styles might have been
providing an impetus to an increase in the demand for this sector,
so the study regarding the production and marketing of milk and
milk products in Punjab was conducted. The study presented a survey
conducted during 2006-2007 in the two districts (Ludhiana and Moga)
of Punjab and the results obtained with regard to production,
consumption and marketed surpluses, marketing channels for milk and
milk products, factors determining channel choices and the various
problems faced by the milk producers and the market players were
discussed. Several conclusions were made.
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